Table 1

 Aneuploidy in different malignancies

MalignancyChromosomal alteration
Acute myeloid leukaemia3Gain of chromosome 8 (13%) and loss of chromosome 7 (10%)
Chronic lymphocytic leukaemia4Trisomy 12 (30%)
Acute lymphatic leukaemia5Gain of chromosomes 4, 6, 10, 14, 17, 18, 20
Non-Hodgkin lymphoma6Trisomy 12
Bladder carcinoma6Trisomy 7, monosomy 8
Malignant fibrous histiocytoma6Gain of chromosome 19
Lung carcinoma7Loss of Y chromosome and gain of chromosome 7
Breast carcinoma8Trisomy 7, 8, 18, 20
Uterine carcinoma9,10Diploid range, trisomy 10, gain of chromosomes 2, 7, 12
Ovarian carcinoma11Loss of chromosomes 22, 17, 13, 14, 8 and gain of chromosome 22
Prostatic carcinoma12,13Normal karyotype, loss of Y chromosome and gain of chromosomes 7, 14, 3
Colonic carcinoma14Gain of chromosomes 3, 4, 6, 11, 12, 13, 15, 16
Loss of chromosomes 14, 15, 18