Comparative summary of course of murine genital tract infection with different clinically characterised Chlamydia trachomatis serovar E isolates
| Strain | Incidence of infection* | Median duration of infection† | Vaginal PMN content during the acute phase of infection‡ | Upper genital tract infection§ | ||||
|---|---|---|---|---|---|---|---|---|
| Neg | Trace | +/++ | Upper cervix | Uterine horns | Ovaries and tubes | |||
| No significant differences were obtained for the parameters evaluated. | ||||||||
| *An animal was considered infected if one or more vaginal samples was positive either by culture or PCR; †the duration of infection for a given animal was assigned as the last positive vaginal sample, with the median duration determined from only the infected animals in a group; ‡PMN responses were determined during the first two weeks of infection as instructed by the manufacturer; the percentage of the total number of specimens tested during this period within each category of response is shown; §a tissue was considered infected if positive either by culture or PCR. | ||||||||
| PCR, polymerase chain reaction; PMN, polymorphonuclear granulocytes. | ||||||||
| S1 | 6/8 | 31.5 | 22% | 58% | 20% | 3/4 | 2/4 | 0/4 |
| S2 | 6/8 | 31.5 | 20% | 62% | 18% | 2/4 | 3/4 | 0/4 |
| Combined | 12/16 | 31.5 | 21% | 60% | 19% | 5/8 | 5/8 | 0/8 |
| AS1 | 8/8 | 35 | 15% | 60% | 25% | 2/4 | 3/4 | 0/4 |
| AS2 | 5/8 | 35 | 20% | 55% | 25% | 2/4 | 2/4 | 0/4 |
| Combined | 13/16 | 35 | 18% | 57% | 25% | 4/8 | 5/8 | 0/8 |