Observed range of haemoglobin S percentage in individuals with sickle cell trait divided into three groups by inspection of the data, with of without globin chain synthesis data, but without analysis of globin genes
| N | Postulated genotype | Method | Ref | ||
|---|---|---|---|---|---|
| αα/αα | −α/αα | −α/−α | |||
| NS, not specified. | |||||
| Electrophoresis on polyacrylamide gel or cellulose acetate followed by elution | 5 | ||||
| NS | 37–50 | 30–36 | 20–29 | NS | 6 |
| 75 | >38 | 31–38 | <31 | Column chromatography | 7 |
| 56 | >38 | 31–38 | <31 | Column chromatography | 8 |
| 171 | 35–45 | 28–35 | <28 | Cellulose acetate electrophoresis and elution | 9 |