Manual | Automated (supervised) | |
---|---|---|
*Most of the hands on time relates to the preselection of cells from the digitally stored images; the time spend by the pathologist for cytopathological confirmation is very small. | ||
H&E, haematoxylin and eosin; IHC, immunohistochemistry; SLN, sentinel lymph node. | ||
Staining | H&E or IHC | IHC |
Sensitivity to detect micrometastases | Low to moderate | High |
Hands on time/section | 30–60 sec | 1 min* |
Costs of hardware | 20 k$ | 100 k$ |
Digital documentation | No | Yes |
Fun factor | Low | High |
Fatigue factor | High | Low |
Reproducibility | Good | Very good |