n | HIF-1α staining pattern* | p Value (χ^{2}) | ||
---|---|---|---|---|

Diffuse | Necrotic | |||

*One case, which was grouped with the perinecrotic cases, showed both diffuse and perinecrotic expression. | ||||

CA IX, carbonic anhydrase IX; GLUT-1, glucose transporter 1; HIF-1α, hypoxia inducible factor 1α. | ||||

Grade | ||||

I | 15 | 13 | 2 | |

II | 30 | 25 | 5 | |

III | 43 | 23 | 20 | 0.007 |

CA IX | ||||

Negative | 67 | 55 | 12 | |

Positive | 21 | 6 | 15 | <0.001 |

GLUT-1 | ||||

Negative | 46 | 41 | 5 | |

Positive | 42 | 20 | 22 | <0.001 |