Alterations of the mononuclear inflammatory cells in the BALF, blood, and the skin of patients with SSc and healthy controls
| SSc (n = 19) | lSSc (n = 10) | dSSc (n = 9) | HC (n = 6) | p Value | |
|---|---|---|---|---|---|
| Values are mean (SD). | |||||
| The p values are for patients with SSc compared with HCs. | |||||
| BALF, bronchoalveolar lavage fluid; dSSc, diffuse systemic sclerosis; HC, healthy controls; lSSc, limited systemic sclerosis; SSc, systemic sclerosis. | |||||
| BALF | |||||
| Total | 238 (49.8) | 214 (32.8) | 260 (53.7) | 157.5 (59.40 | <0.05 |
| Monocytes | 80.7 (3.2) | 81.2 (4.5) | 79.6 (8.8) | 90.2 (1.5) | NS |
| Lymphocytes | 13.5 (1.3) | 14.2 (4.1) | 12.9 (5.8) | 6.5 (2.1) | <0.05 |
| Neutrophils | 4.3 (0.6) | 4.1 (1.2) | 4.7 (2.0) | 2.2 (0.3) | <0.05 |
| Eosinophils | 1.5 (1.6) | 1.1 (0.6) | 1.1 (0.9) | 1.1 (0.6) | NS |
| Blood | |||||
| Total | 8.3 (3.1) | 8.3 (3.8) | 8.3 (2.5) | 6.1 (1.01) | NS |
| Monocytes | 5.0 (3.6) | 4.1 (2.2) | 5.9 (4.6) | 4.7 (1.2) | NS |
| Lymphocytes | 37.3 (15.8) | 42.0 (14.5) | 32.1 (16.4) | 40.8 (5.8) | NS |
| Neutrophils | 52.0 (18.5) | 46.4 (16.8) | 57.6 (19.6) | 46.5 (7.7) | NS |
| Eosinophils | 5.8 (3.8) | 7.4 (3.4) | 4.1 (3.8) | 1.0 (1.0) | <0.05 |
| Skin | |||||
| Total | 3.9 (3.6) | 3.6 (3.4) | 4.3 (4.0) | 2.1 (1.7) | NS |
| Histiocytes | 10.1 (3.9) | 10.9 (4.4) | 10.7 (4.2) | 2.0 (0.3) | <0.05 |
| Lymphocytes | 4.2 (1.8) | 2.9 (2.2) | 5.8 (1.7) | 7.5 (1.8) | <0.05 |
| Neutrophils | 0.3 (0.3) | 0.3 (0.3) | 0.3 (0.3) | 0.0 (0.0) | <0.05 |
| Eosinophils | 0.3 (0.2) | 0.3 (0.3) | 0.3 (0.3) | 0.0 (0.0) | <0.05 |