HPV and p53 codon 72 genotype distribution in normal controls and patients with cervical carcinoma at different histological stages
| Cytology/Histology | N | HPV-16+ | HPV-18+ | p53 Arg /Arg | p53 Arg/Pro | p53 Pro/Pro |
|---|---|---|---|---|---|---|
| N, number of individuals analysed. | ||||||
| HPV, human papillomavirus. | ||||||
| Normal | 94 | 11 (11.7%) | 6 (6.4%) | 14 (15.0%) | 51 (54.2%) | 29 (30.8%) |
| Dysplasia | 3 | 1 (33.3%) | 1 (33.3%) | 0 (0%) | 3 (100%) | 0 (0%) |
| Cancer stage I+II | 39 | 22 (56.4%) | 9 (23.1%) | 11 (28.2%) | 20 (51.3%) | 8 (20.5%) |
| Cancer stage III+IV | 19 | 14 (73.7%) | 5 (26.3%) | 8 (42.1%) | 7 (36.8%) | 4 (21.1%) |