Extended haplotype frequencies for patients and normal controls (16 bp–Bst UI–Nci I)
| Population (n) | p53 haplotypes | p Value | |||||
|---|---|---|---|---|---|---|---|
| 1–2–2 (%) | 1–1–2 (%) | 2–1–1 (%) | 1–1–1 (%) | 2–1–2 (%) | 1–2–1 (%) | ||
| N, number of chromosomes analysed. | |||||||
| Haplotypes are in the order of: intron 3–codon 72–intron 6. | |||||||
| 1 at an individual locus indicates the absence of a 16 bp duplication at intron 3, a proline at Bst UI, and the absence of Nci I at intron 6. | |||||||
| 2 at individual locus indicates the presence of a 16 bp duplication at intron 3, an arginine at Bst UI, and the presence of Nci I at intron 6. | |||||||
| Normal (168) | 70 (41.7) | 51 (30.4) | 22 (13.1) | 14 (8.3) | 11 (6.5) | 0 (0) | 0.042 |
| Patient (104) | 54 (51.9) | 25 (24.0) | 7 (6.7) | 7 (6.7) | 7 (6.7) | 4 (3.8) | |