Characteristics of the 38 patients with clinically relevant clostridium bacteraemia
| Patient | Sex/Age | Underlying disease | Diagnosis | Blood culture isolate | CA/HA | Positive blood cultures (n) | Other bacteria recovered in blood culture | Outcome |
|---|---|---|---|---|---|---|---|---|
| AC, acute cholangitis; AF, atrial fibrillation; ALL, acute lymphoblastic leukaemia; AML, acute myeloid leukaemia; Ca, carcinoma; CA, community acquired; COPD, chronic obstructive pulmonary disease; CRF, chronic renal failure; CVA, cerebrovascular accident; DM, diabetes mellitus; F, female; GIB, gastrointestinal bleeding; HA, hospital acquired; HCC, hepatocellular carcinoma; HT, hypertension; IHD, ischaemic heart disease; IO, intestinal obstruction; IVDA, intravenous drug abuse; M, male; PU, peptic ulcer; PVD, peripheral vascular disease; RA, rheumatoid arthritis; RPC, recurrent pyogenic cholangitis; SSS, sick sinus syndrome; TB, tuberculosis. | ||||||||
| 1 | F/86 | Gallstones | Infected bed sore | C perfringens | CA | 1 | None | Cured |
| 2 | F/83 | Ca cervix with liver metastasis, gallstones | Primary bacteraemia | C perfringens | HA | 1 | None | Cured |
| 3 | M/59 | Liver cirrhosis, hepatic encephalopathy | Primary bacteraemia | C perfringens | CA | 1 | None | Died |
| 4 | F/44 | Carcinoid tumour with liver metastasis | AC | C perfringens | CA | 1 | Klebsiella pneumoniae | Died |
| 5 | M/92 | HT, dementia, gallstones | AC | C perfringens | CA | 1 | Escherichia coli | Cured |
| 6 | F/77 | HT, osteoporosis | Primary bacteraemia | C perfringens | CA | 1 | None | Cured |
| 7 | M/1 | None | Intussusception | C perfringens | CA | 1 | E coli, K pneumoniae, Enterococcus gallinarum | Died |
| 8 | M/26 | IVDA | Gas gangrene of right leg | C perfringens | CA | 2 | None | Cured |
| 9 | F/73 | Ca colon, HT, TB | Intra-abdominal abscess | C perfringens | CA | 1 | None | Cured |
| 10 | M/79 | Cholangiocarcinoma, gallstones | AC | C perfringens | CA | 1 | Aeromonas sobria | Cured |
| 11 | F/88 | Dementia, rectovaginal and vesicovaginal fistula | Infected fistula | C perfringens | CA | 1 | None | Cured |
| 12 | M/78 | CVA, SSS, RPC | AC | C perfringens | CA | 2 | Enterobacter aerogenes | Cured |
| 13 | F/75 | Gallstones | Acute cholecystitis | C perfringens | CA | 1 | E coli | Cured |
| 14 | M/69 | DM, gallstones, fatty liver, HT, IHD, hyperlipidaemia, PU | Acute cholecystitis | C perfringens | CA | 1 | E coli | Cured |
| 15 | F/69 | RA, Ca cervix, irradiation proctitis, cystitis, hydronephrosis | Primary bacteraemia | C perfringens | CA | 1 | None | Cured |
| 16 | M/68 | HT, PU | Acute cholecystitis | C perfringens | CA | 1 | E coli | Died |
| 17 | M/95 | Gallstones, CVA | AC and acute cholecystitis | C perfringens | CA | 1 | E coli | Cured |
| 18 | M/72 | DM, HT, PVD, alcoholism | Wet gangrene of ?lower limbs | C perfringens | CA | 1 | Streptococcus dysgalactiae subsp. dysgalactiae | Cured |
| 19 | M/88 | Liver cirrhosis, COPD, HT, DM, CVA, CRF | Primary bacteraemia | C perfringens | CA | 1 | None | Cured |
| 20 | M/84 | None | AC, subphrenic abscess | C perfringens | CA | 1 | None | Cured |
| 21 | F/70 | Sjogren’s syndrome, osteoporosis, PVD, big toe gangrene, AF | Right foot gangrene | C perfringens | HA | 1 | None | Died |
| 22 | M/72 | HT, DM, COPD, CRF, RPC, old TB, gallstones | AC | C perfringens | CA | 1 | E coli, K pneumoniae, Proteus vulgaris | Died |
| 23 | M/64 | IHD, DM, HT, colonic diverticulitum | Acute diverticulitis | C perfringens | CA | 2 | E coli, K pneumoniae | Cured |
| 24 | F/59 | RPC | AC | C perfringens | CA | 1 | E coli | Cured |
| 25 | M/82 | Ca pancreas with peritoneal carcinomatosis, GIB, IO | Primary bacteraemia | C perfringens | CA | 1 | None | Cured |
| 26 | M/90 | None | Aspiration pneumonia | C perfringens | CA | 1 | None | Cured |
| 27 | M/46 | CRF, liver cirrhosis, hyperparathyroidism | Spontaneous bacterial peritonitis | C perfringens | CA | 1 | None | Died |
| 28 | F/89 | IHD, CVA, AF, bronchiectasis, pyometra | Primary bacteraemia | C perfringens | CA | 1 | None | Cured |
| 29 | M/46 | Renal cell Ca with lung and peritoneal metastasis, GIB | Primary bacteraemia | C perfringens | HA | 1 | E coli, K pneumoniae | Died |
| 30 | F/84 | DM, HT, gallstones | Acute cholecystitis | C perfringens | CA | 1 | E coli, K pneumoniae | Cured |
| 31 | M/54 | HCC, history of liver abscess, GIB | Primary bacteraemia | C ramosum | CA | 1 | Bacteroides fragilis group | Died |
| 32 | M/71 | CVA | Infected bed sore | C ramosum | HA | 1 | Proteus mirabilis | Cured |
| 33 | M/78 | Ca sigmoid with liver metastasis | Primary bacteraemia | C ramosum | HA | 1 | E coli, Pseudomonas aeruginosa, Enterococcus avium | Died |
| 34 | F/75 | Dementia, asthma, HT, DM, uterine prolapse | Primary bacteraemia | C disporicum | HA | 1 | None | Cured |
| 35 | M/6m | None | Intussusception with peritonitis | C paraputrificum | CA | 1 | None | Cured |
| 36 | F/40 | AML, dental caries, neutropenic fever | Primary bacteraemia | C septicum | CA | 1 | None | Cured |
| 37 | F/12 | ALL, mucositis, neutropenic fever | Primary bacteraemia | C tertium | HA | 2 | None | Cured |
| 38 | M/1m | Prematurity | Necrotising enterocolitis | C difficile | HA | 1 | Enterobacter cloacae | Died |