Table 1

Main protein types causing amyloidosis with the emphasis on cardiovascular system involvement

Amyloid protein	Precursor	Distribution	Syndrome
Proteins involved in the cardiovascular system are in bold.
AL	Immunoglobulin light chain	Systemic/localised	Primary/myeloma associated
AH	Immunoglobulin heavy chain	Systemic/localised	Primary/myeloma associated
AA	Serum amyloid A	Systemic	Secondary
Aβ₂ Microglobulin	β₂ Microglobulin	Systemic	Secondary
ATTR	Transthyretin	Systemic	Senile systemic/familial
AANF	Atrial natriuretic factor	Localised	Atrial isolated
AApoA-I	Apolipoprotein A-I	Localised/systemic	Aortic/familial
AApoA-II	Apolipoprotein A-II	Systemic	Familial
Amed	Lactadherin	Localised	Aortic
Agel	Gelsolin	Systemic	Familial
Alys	Lysozyme	Systemic	Familial
Afib	Fibrinogen α chain	Systemic	Familial
Acys	Cystatin C	Systemic	Familial
Aβ	Aβ Protein precursor	Localised	Alzheimer’s disease, aging
AprP	Prion protein	Localised	Spongiform encephalopathies
Abri	ABri protein precursor	Localised	Familial dementia
Acal	(Pro)calcitonin	Localised	Thyroid tumours derived from C cells
AIAPP	Islet amyloid polypeptide	Localised	Langerhans islets, insulinomas
Apro	Prolactin	Localised	Prolactinomas, pituitary in elderly
Ains	Insulin	Localised	Iatrogenic
Aker	Kerato-epithelin	Localised	Familial, cornea
Alac	Lactoferrin	Localised	Familial, cornea