Table 3
 Polymorphisms associated with advanced prostate cancer risk
Gene
Chromosomal locus
Function
Vitamin D receptor
13q
Promotes the differentiation and growth arrest of prostate cancer cells in vitro
CDKN1A (p21)
6p
Belong to the Cip/Kip family and functions as an important cell cycle gatekeeper
CDKN1B (p27)
12p