Comparison between tumour and normal adjacent mucosa for all examined genetic markers
| Tumour (n = 48) | Distal mucosa (n = 20) | p Value | ||||
|---|---|---|---|---|---|---|
| Numbers in parentheses represent percentages. Significance was measured using the Mann-Whitney test (non-parametric test). | ||||||
| HE, heterozygous deletion; HO, homozygous deletion; NS, not significant. | ||||||
| Chromosome 3 monosomy | 21 (43.7) | 7 (35.0) | NS | |||
| Chromosome 3 polysomy | 19 (39.5) | 4 (20.0) | NS | |||
| Chromosome 7 monosomy | 21 (43.7) | 1 (5.0) | 0.004 | |||
| Chromosome 7 polysomy | 21 (43.7) | 3 (15.0) | 0.037 | |||
| Chromosome 9 monosomy | 33 (68.7) | 11 (55.0) | NS | |||
| Chromosome 9 polysomy | 10 (20.8) | 1 (5.0) | NS | |||
| Chromosome 17 monosomy | 18 (37.5) | 1 (5.0) | 0.015 | |||
| Chromosome 17 polysomy | 20 (41.6) | 5 (25.0) | NS | |||
| p16 HO | 4 (8.3) | 0 (0.0) | NS | |||
| p16 HE | 32 (66.6) | 17 (85.0) | NS | |||
| p53 HO | 4 (8.3) | 1 (5.0) | NS | |||
| p53 HE | 27 (56.2) | 17 (85.0) | NS | |||
| RB1 HO | 6 (12.5) | 2 (10.0) | NS | |||
| RB1 HE | 39 (81.2) | 15 (75.0) | NS | |||
| HER-2 amplification | 7 (14.5) | 0 (0.0) | NS | |||