Table 3

 Univariate regression analysis, Cox proportional hazards model

RR95% CIp Value
*Significant.
AI, apoptotic index; CI, confidence interval; HPV, human papillomavirus; LI, labelling index; MI, MIB-1 labelling index; RR, relative risk.
Age (⩾60 years)0.7310.296 to 1.7440.4646
Sex (male)0.7370.134 to 2.4870.4611
pT (pT3 or 4)3.1910.038 to 0.6720.0123*
Lymph node metastasis (positive)3.4190.030 to 0.6020.0087*
Grade (G2 or G3)0.5390.248 to 2.2100.5900
MI (⩾47)2.2050.152 to 0.8950.0275*
AI (<3.2)2.2970.142 to 0.8570.0216*
E2F-1 LI (⩾25)2.8570.139 to 0.8820.0259*
p21 LI (<10)0.7120.199 to 1.5010.2413
p16 LI (<70)0.3520.608 to 3.4400.7250
pRb LI (<20)0.7120.492 to 4.5700.4765
Cyclin D1 (⩾10)0.0790.409 to 2.2820.9367
p53 mutation (positive)1.2220.718 to 4.1560.2218
HPV infection (positive)1.0530.654 to 4.0940.2924