Table 5

 Immunohistochemical staining patterns of p21, p16, and p53 in patients with non-small cell lung cancer

Cyclin D1pRb2/p130p16No. of patientsGroup
Group A, no or only one adverse prognostic factor; group B, two adverse prognostic factors; group C, three adverse prognostic factors.
++24
+22A (59)
+4
+++9
++18
++6B (25)
1
+21C (21)