The modified Marsh–Oberhuber classification
Marsh 0 | Marsh 1 | Marsh 2 | Marsh 3 | Marsh 4† | |||
---|---|---|---|---|---|---|---|
3a | 3b | 3c | |||||
IEL, intraepithelial lymphocytes. | |||||||
*Number of intraepithelial lymphocytes per 100 enterocytes. | |||||||
†This category is principally included for historic purposes. | |||||||
IEL count* | <30/100 | >30/100 | >30/100 | >30/100 | >30/100 | >30/100 | <30/100 |
Crypt hyperplasia | − | − | + | + | + | + | − |
Villous atrophy | − | − | − | Mild | Moderate | Total | Total |
Pre-infiltrative | Infiltrative | Infiltrative-hyperplastic | Flat destructive | Atrophic-hypoplastic |