Antibodies and immunostaining results
| Antigens | Cells in close contact with the stroma | Cells in the centre of nests | Cells in between |
|---|---|---|---|
| CK, cytokeratin; PSA, prostate specific antigen; SMA, α smooth muscle actin. | |||
| 34βE12 | Positive | Negative | Positive |
| p63 | Positive | Negative | Positive |
| bcl-2 | Positive | Negative | Positive |
| CK20 | Negative | Negative | Negative |
| SMA | Positive (focal) | Negative | Negative |
| S-100 protein | Positive (focal) | Negative | Negative |
| AE1/AE3 | Negative | Positive | Negative |
| CK7 | Negative | Positive | Negative |
| PSA | Negative | Positive (focal) | Negative |
| Ki-67 | Positive (very few) | Negative | Positive |
| Laminin | Positive | Negative | Negative |
| c-erbB-2 oncoprotein | Negative | Positive | Positive |
| Chromogranin | Negative | Negative | Negative |