Genes that are differentially expressed in MPNST and BPNST
| Gene | p Value* | p Value† | MPNST:BPNST‡ |
|---|---|---|---|
| *Derived from the t test; †derived from the permutation test; ‡average. | |||
| BPNST, benign peripheral nerve sheath tumour; IGFBP6, insulin-like growth factor binding protein 6; MPNST, malignant peripheral nerve sheath tumour. | |||
| Genes upregulated in MPNST | |||
| Keratin 18 | 0.0078 | 0.0065 | 3.3 |
| Survivin (baculoviral IAP repeat containing 5) | 0.0023 | 0.0043 | 3 |
| Tenascin C (hexabrachion, cytotactin) | 0.013 | 0.017 | 2.8 |
| Adenosine deaminase | 0.0018 | 0.0043 | 2.4 |
| Collagen, type VI, α3 | 0.0083 | 0.024 | 2.2 |
| Collagen, type VII, α1 (epidermolysis bullosa, dystrophic, dominant, and recessive) | 0.012 | 0.0087 | 2.2 |
| Downregulated in MPNST | |||
| IGFBP6 | 0.0037 | 0.0022 | 0.49 |