Case | Survivin (expression)* | Survivin (RT-PCR) | Survivin (IHC) | Tenascin C (expression)* | Tenascin C (RT-PCR) | Tenascin C (tumour centre; IHC) | Tenascin C (invasive front, collagen; IHC) |
---|---|---|---|---|---|---|---|
*The ratio between the samples and control human RNA (Universal Human Reference RNA; Stratagene, La Jolla, California, USA); †evaluation was impossible because only tumour tissue was excised and no invasive front or stromal tissue were seen. | |||||||
IHC, immunohistochemistry; MPNST, malignant peripheral nerve sheath tumour; ND, not done; RT-PCR, reverse transcription polymerase chain reaction. | |||||||
MPNST | |||||||
1 | 1.46 | − | 3+ | 0.82 | − | − | + |
2 | 1.2 | + | + | 0.34 | + | + | 3+ |
3 | 0.78 | + | + | 0.53 | − | − | 2+ |
4 | 0.97 | + | + | 1.08 | + | − | 2+ |
5 | 1.61 | + | 2+ | 1.01 | + | + | 2+ |
6 | 1.04 | ND | ND | 1.26 | ND | − | + |
7 | ND | ND | − | ND | ND | 2+ | 3+ |
8 | ND | ND | + | ND | ND | − | 2+ |
9 | ND | ND | − | ND | ND | 2+ | Not determined† |
Schwannoma | |||||||
10 | 0.59 | − | − | 0.26 | − | − | + |
11 | 0.44 | ND | + | 0.35 | ND | − | + |
12 | 0.26 | − | − | 0.29 | − | − | 2+ |
13 | ND | ND | − | ND | ND | − | − |
14 | ND | ND | − | ND | ND | − | 2+ |
Neurofibroma | |||||||
15 | 0.58 | ND | − | 0.21 | ND | − | 2+ |
16 | 0.46 | ND | ND | 0.4 | ND | − | + |
17 | ND | ND | + | ND | ND | − | − |
18 | ND | ND | − | ND | ND | − | − |