Table 1 Overview of morphological classification, ploidy and immunohistochemical analyses of tissue samples gathered from 31 patients with longstanding UC

Diagnosis	Patients	Samples	Samples for ploidy analysis	Aneuploid samples	∗Protein expression (%)
Diagnosis	Patients	Samples	Samples for ploidy analysis	Aneuploid samples	Aurora A	BUB1B	Mad2	Ki67
Normal	10	10	0	–	13	4	19	14
No dysplasia	30	165	159	30 (19%)	40	7	43	27
Ind. dysplasia	12	30	29	8 (28%)	31	10	46	27
Dysplasia	14	33	32	9 (28%)	24	10	41	28
Cancer	8	11	11	6 (55%)	45	12	32	25
Total	‡	249	231	53 (23%)
p-Value†					<0.001	<0.001	0.8	0.18

∗Reflects the mean % of positive epithelial cells for each sample.
†p-Value describing the difference in protein expression in dysplastic versus non-dyplastic mucosa.
‡Total 31 patients, 19 patients had ⩾2 morphological diagnoses in their colons.