Table 2

 Suggested thresholds on confirmation of a rise in platelet count (× 109/l)

*Aspirin has been shown to be efficacious in primary thrombocythaemia, but the level at which it should be initiated is unknown.22
<450No further action required
450–600If symptoms, refer
If asymptomatic, investigate
600–1000If no secondary cause, refer
Consider aspirin*
>1000Refer. Avoid aspirin unless thrombotic complications present