Prevalence of selected histological parameters in patients with IT and CD
| Histopathological parameters | All patients | All biopsy specimens | Endoscopically abnormal mucosa | Endoscopically normal mucosa | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IT (n = 18) | CD (n = 25) | p Value | IT (n = 41) | CD (n = 103) | p Value | IT (n = 28) | CD (n = 77) | p Value | IT (n = 13) | CD (n = 26) | p Value | |
| CD, Crohn’s disease; IT, intestinal tuberculosis; –, not determined. | ||||||||||||
| *p<0.05. | ||||||||||||
| Granulomas | 78% | 28% | 0.0035* | 46% | 14% | 0* | 56% | 16% | 0* | 7% | 7% | 0.7 |
| Average number of granulomas | 6.5 | 2.5 | 0.054 | 2.85 | 0.6 | 0.0007* | 4.11 | 0.7 | 0* | 0.15 | 0.3 | 0.988 |
| Granulomas ⩾5 per biopsy site | 44% | 24% | 0.28 | 20% | 7% | 0.029* | 29% | 8% | 0.01* | 0 | 0 | – |
| Granulomas ⩾10 per biopsy site | 33% | 0 | 0.003* | 15% | 0 | 0.0005* | 21% | 0 | 0.0003* | 0 | 0 | – |
| Granulomas >0.05 mm2 | 67% | 8% | 0.0002* | 31% | 2% | 0* | 46% | 2% | 0* | 0 | 0 | – |
| Confluent granulomas | 50% | 0 | 0* | 24% | 0 | 0* | 36% | 0 | 0* | 0 | 0 | – |
| Caseous necrosis | 22% | 0 | 0.025* | 10% | 0 | 0.006* | 14% | 0 | 0.004* | 0 | 0 | – |
| Mucosal granulomas | 44% | 40% | 0.4 | 22% | 13% | 0.25 | – | – | – | – | – | |
| Submucosal granulomas | 44% | 12% | 0.02* | 22% | 4% | 0.002* | – | – | – | – | – | |
| Granulation tissue granulomas | 26% | 8% | 0.16 | 10% | 2% | 0.052* | – | – | – | – | – | |
| Ulcer with epithelioid histiocytes | 61% | 8% | 0.0002* | 30% | 2% | 0* | 39% | 3% | 0* | 0 | 0 | – |
| Disproportionate submucosal chronic inflammation | 67% | 10% | 0.02* | 55% | 5% | 0.004* | 60% | 7% | 0.007* | 0 | 0 | – |