Wotherspoon scoring system for scoring gastric lymphoid infiltrates20
| Score | Diagnosis | Histological features |
|---|---|---|
| MALT, mucosa-associated lymphoid tissue. | ||
| 0 | Normal | Scattered plasma cells in lamina propria. No lymphoid follicles |
| 1 | Chronic active gastritis | Small clusters of lymphocytes in lamina propria. No lymphoid follicles. No lymphoepithelial lesions |
| 2 | Chronic active gastritis with florid lymphoid follicle formation | Prominent lymphoid follicles with a surrounding mantle zone and plasma cells. No lymphoepithelial lesions |
| 3 | Suspicious lymphoid infiltrate, probably reactive | Lymphoid follicles surrounded by small lymphocytes that infiltrate diffusely in lamina propria and occasionally into the epithelium |
| 4 | Suspicious lymphoid infiltrate, probably lymphoma | Lymphoid follicles surrounded by marginal-zone cells that infiltrate diffusely in lamina propria and into the epithelium in small groups |
| 5 | MALT lymphoma | Presence of dense diffuse infiltrate of marginal-zone cells in lamina propria with prominent lymphoepithelial lesions |