Correlation of STAT3 expression with STAT3-inducible targets in colorectal tumour cells
| Marker | STAT3 mRNA | STAT3 protein | P-STAT3 protein | ||
|---|---|---|---|---|---|
| cyt | nuc | cyt | nuc | ||
| cyt, cytoplasmic; nuc, nuclear; STAT3, signal transducers and activators of transcription. | |||||
| Cyclin D1 mRNA | 0.018 | 0.024 (cyt) | |||
| Survivin mRNA | 0.003 | 0.019 (cyt), | 0.001 (cyt) | 0.001 (nuc) | |
| Survivin protein | 0.039 (nuc) | 0.049 (nuc) | |||
| Bcl-xl mRNA | 0.003 | 0.024 | 0.038 | ||
| Bcl-xl protein | 0.001 | ||||
| Mcl-1 mRNA | 0.05 | ||||
| Ki-67 protein | 0.017 | ||||