Complementarity of different multiplex PCR targets for clonality detection in 49 germinal centre/post-germinal centre malignancies
| Multiplex PCR tubes | DLBCL (%) | FL (%) |
|---|---|---|
| DLBCL, diffuse large B cell lymphoma; FL, follicular lymphoma; FR, framework. | ||
| IGH VH-JH FR1 | 5/23 (22) | 14/26 (54) |
| IGH VH-JH FR2 | 13/23 (56) | 22/26 (84) |
| IGH VH-JH FR3 | 12/23 (52) | 14/26 (54) |
| IGH VH-JH (FR 1-3) | 17/23 (74) | 25/26 (96) |
| IGH DH-JH | 8/23 (35) | 6/26 (23) |
| IGH VH-JH (FR 1-3)+DH-JH | 22/23 (96) | 26/26 (100) |
| IGκ | 17/23 (74) | 24/26 (92) |
| IGλ | 3/23 (13) | 4/26 (15) |
| IGH VH-JH (FR 1-3)+DH-JH+IGκ+IGλ | 23/23 (100) | 26/26 (100) |
| t(14;18) | 9/23 (39) | 17/26 (65) |
| IGH VH-JH (FR 1-3)+DH-JH+IGK+t(14;18) | 23/23 (100) | 26/26 (100) |