α-Globin genotypes of 100 patients with Hb H disease
| No | |
|---|---|
| *Two individuals had concomitant β-thalassaemia trait (one −−SEA/−α3.7, one −−SEA/αQuong Szeα) | |
| †Three are brother and sister. | |
| ‡Two are brother and sister. | |
| §Two are brother and sister. | |
| Deletional | |
| (−−SEA/−α3.7) | 43† |
| (−−SEA/−α4.2) | 24 |
| (−−SEA/−α4.2 Q-Thailand [Codon 74 GAC→CAC or Asp→His]) | 3 |
| Subtotal: 70 | |
| Non-deletional | |
| (−−SEA/αConstant Spring [Codon 142 TAA→CAA or Term→Gln]α) | 11 |
| (−−SEA/αQuong Sze [Codon 125 CTG→CCG or Leu→Pro]α) | 9 |
| (−−SEA/αCodon 30 deletion of GAGα) | 3 |
| (−−SEA/αCodon 31 AGG→AAG or Arg→Lysα) | 3‡ |
| (−−SEA/αPoly-A signal AATAAA→AATGAAα) | 2§ |
| (−−SEA/αWestmead [Codon 122 CAC→CAG or His →Gln]α) | 1 |
| (−−Non-SEA/αQuong Sze [Codon 125 CTG→CCG or Leu→Pro]α) | 1 |
| Subtotal: 30 | |
| Total: 100 | |