Serum triglyceride category | ATP III criteria | Treatment goals | Treatment algorithm117 |
Normal | <1.7 mmol/l | – | – |
Borderline | 1.7–2.2 mmol/l | Achieve LDL cholesterol targets | Weight reduction, smoking cessation, exercise, reduce alcohol intake, moderate carbohydrate intake |
High | 2.3–5.5 mmol/l | Primary: achieve LDL cholesterol targets Secondary: achieve non-HDL targets | Lifestyle changes as above plus drugs to attain LDL and non-HDL cholesterol targets, manage hyperglycaemia |
Very high | >5.5 mmol/l | Primary: prevent pancreatitis Secondary: prevent CVD | Lifestyle changes with very low fat diet (<15% of calories) if risk of pancreatitis plus triglyceride lowering drug therapy including fish oil |
CVD, cardiovascular disease; HDL, high density lipoprotein; LDL, low density lipoprotein.