Glandular spaces | Slit-like | Round, punched-out |
Psammoma bodies | Common | Rare |
Tumour giant cells | Common | Rare |
Papillae | Small, complex with budding | Longer and broader |
Adenofibromatous growth pattern | Rare | Common |
Squamous elements | Rare | Common |
Endometriosis | Rare | Common |
|
Immunohistochemistry |
WT1 | Diffuse positive | Negative or focally positive |
p53 | Diffuse positive | Negative, focally or diffuse positive |
p16 | Diffuse positive | Negative or focally positive |
Vimentin | Negative | Sometimes positive |
β-Catenin | Membranous staining | Membranous and, in some cases, nuclear positivity |