Table 1 Distinction between poorly differential serous and poorly differentiated endometrioid adenocarcinoma
MorphologySerousEndometrioid
Glandular spacesSlit-likeRound, punched-out
Psammoma bodiesCommonRare
Tumour giant cellsCommonRare
PapillaeSmall, complex with buddingLonger and broader
Adenofibromatous growth patternRareCommon
Squamous elementsRareCommon
EndometriosisRareCommon
Immunohistochemistry
WT1Diffuse positiveNegative or focally positive
p53Diffuse positiveNegative, focally or diffuse positive
p16Diffuse positiveNegative or focally positive
VimentinNegativeSometimes positive
β-CateninMembranous stainingMembranous and, in some cases, nuclear positivity