Table 3 Univariate analysis of various parameters (overall survival)
ParameterComparisonHR (95% CI)p value
Nodal statusN0 vs N +4.65 (1.83 to 11.83)0.0013
Tumour sizeT1 vs T21.23 (0.65 to 2.33)NS
T1 vs T31.46 (0.85 to 2.52)
FOXA1FOXA1pos vs FOXA1neg0.36 (0.17 to 0.75)0.0044
ERER+ vs ER−0.31 (0.17 to 0.58)0.0001
Tumour gradeGrade I/II vs grade III2.26 (0.08 to 4.72)0.0307
HER2/neuHER2+ vs HER2−1.60 (0.76 to 3.36)NS
PRPR+ vs PR−0.34 (0.18 to 0.63)0.0005
Any basal markerPositive vs negative2.83 (1.49 to 5.39)0.0010
p53p53+ vs p53−2.81 (1.49 to 5.33)0.0010
MIB1Low vs intermediate1.40 (0.65 to 3.02)0.0023
Low vs high1.96 (1.31 to 2.93)
Cyclin D1Intermediate vs low0.59 (0.23 to 1.48)0.0049
High vs low0.57 (0.39 to 0.85)
Molecular subgroupHER2 vs luminal2.25 (1.01 to 4.97)0.0007
Basal vs luminal1.83 (1.26 to 2.66)
  • FOXA1, forkhead box A1; HR, hazard ratio; ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; FOXA1pos, high level of FOXA1 expression (score greater than 3); FOXA1neg, low level of FOXA1 expression (score 3 or less).