Table 2 Associations between oestrogen receptors and clinicopathological parameters

Variable	ERβ−n = 174	ERβ+n = 177	p value‡	ERα−n = 72	ERα+n = 407	p value‡
Age, years
Median (range)	65 (28–64)	66 (27–96)	0.71	59.5 (27–63)	66 (28–68)	0.005**
<40	9	6	0.18	5	12	0.04*
40–49	26	20		12	48
50–	139	151		55	347
Size, mm
Median (range)	18 (1–99)	18(0.5–100)	0.22	20 (1–99)	17 (0.5–100)	0.10
⩽20	97	108	0.32	37	259	0.05*
>20	77	69		35	148
NHG†
I	37	33	0.85	3	117	0.001**
II	71	78		17	181
III	66	65		52	108
Nodal status
N0	92	99	0.55	42	226	0.57
N1	64	60		22	139
HER2
0	59	71	0.64	19	121	0.001**
1+	48	49		17	81
2+	12	15		4	22
3+	9	15		11	12
Ki67
0–10%	58	60	0.94	7	167	<0.001**
11–25%	54	57		17	143
>25%	56	59		46	83
Erα−	38	23	0.02
Erα+	129	152
PgR–	71	51	0.01*	60	81	<0.001**
PgR+	75	97		4	224

‡Mann–Whitney U test for comparison of medians.
Chi Square test for categorised variables.
*p<0.05; **p<0.01.
NHG, Nottingham Histological Grade; ER, oestrogen receptor; PgR, progesterone receptor.