Table 2

Overall and type-specific 16/18/6/11 prevalence of human papillomavirus (HPV) in penile carcinomas by histology subtype

Histology	No. cases	Overall HPV prevalence		Weighted Prevalence (%)*	HPV-16 relative contribution†		HPV-18 relative contribution†		HPV-6/11 relative contribution†
Histology	No. cases	No. positive cases	% (95% CI)	Weighted Prevalence (%)*	No. HPV-16 positive cases	% (95% CI)	No. HPV-18 positive cases	% (95% CI)	No. HPV-6/11 positive cases	% (95% CI)
SCC (unspecified)12 17 18 20 21 22 23 26 27 28 29 30 36 38 39 40 41 54 61	671	333	49.62 (45.7 to 53.4)		251	75.37 (70.4 to 79.9)	40	12.01 (8.7 to 15.9)	17	5.10 (3.0 to 8)
Basaloid SCC13 24 25 33 35 36 38 42	46	35	76.0 (61.2 to 87.4)		23	65.71 (47.8 to 80.8)	0	0 (0.0 to 10.0)	1	2.85 (0.0 to 14.9)
Warty SCC13 24 28 31 33 36 37 38	56	33	58.9 (44.9 to 71.9)		25	75.75 (57.7 to 88.9)	1	3.03 (0.0 to 15.7)	3	9.09 (1.9 to 24.3)
Non-keratinising (typical)19 24 31 32 34 35	117	56	47.8 (38.5 to 57.2)		38	67.85 (54.0 to 79.7)	8	14.28 (6.3 to 26.2)	9	16.07 (7.6 to 28.3)
Mixed warty–basaloid25	19	9	47.3 (24.4 to 71.1)		0	0.0 (0.0 to 33.6)	0	0.0 (0.0 to 33.6)	0	0.0 (0.0 to 33.6)
Keratinising SCC13 16 19 33 34 35 37 42	448	195	43.5 (38.8 to 48.2)		62	31.79 (25.3 to 38.8)	41	21.02 (15.5 to 27.4)	24	12.30 (8.0 to 17.7)
Other SCC mixed13 24 31 33 35 36 37 42	42	14	33.33 (19.5 to 49.5)		11	62.5 (24.4 to 91.4)	1	12.5 (0.3 to 52.6)	0	0.0 (0.0 to 36.9)
Verrucous13 16 17 19 22 23 31 34 35 36 37 38 42	57	14	24.5 (14.1 to 37.7)		5	35.71 (12.7 to 64.8)	1	7.14 (0.1 to 33.8)	2	14.28 (1.7 to 42.8)
Papillary24	10	0	0.0 (0.0 to 30.8)		0	0.0 (0.0 to 30.8)	0	0.0 (0.0 to 30.8)	0	0.0 (0.0 to 30.8)

Total	1466	689	46.99 (44.4 to 49.6)	38.9	415	60.23 (56.4 to 63.9)	92	13.3 (10.9 to 16.1)	56	8.1 (6.2 to 10.4)

*See methods for weights applied.
†Percentage of all subjects tested for the specific type (may include concomitant infection with other types).
SCC, squamous cell carcinoma.