Table 4 Clinical characteristics of patients in relation to BRCA1 and BRCA2 mutations
Clinical dataNumber of patients or ageMutations inBRCA1 andBRCA2 genesWild-typeBRCA1 andBRCA2 genesp Value*
Phenotype
    No with cancer1029840.0001
    No cancer free1174473
Mean age (years)47.7
    Mean age of patients with cancer4645.849.20.006†
    Mean age of cancer-free individuals49.246.750.8

  • *Calculated using two-sided Fisher’s exact test.

  • †Student t test was used to compare means.