Table 1 Comparison of the OLD and the NEW rules
OLD rulesNEW rules
Each Gleason patternModified Gleason pattern (ISUP consensus)Modified Gleason pattern (ISUP consensus)
Biopsy Gleason score for each patientOverall-scoring averaging all positive cores together as if they were one long positive coreHighest-core scoring selecting a core with highest score as the score of each patient
Secondary Gleason pattern occupying less than 5% of the tumourIgnoredReflected if the secondary Gleason pattern is higher than the primary pattern
Tertiary patternIgnoredReflected
  • ISUP, International Society of Urological Pathology.