Table 1 Comparison of HER-2 immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) analysis of 133 breast cancer bone metastases tissue microarrays | HER-2 IHC | No | HER-2 FISH |
| Equivocal(ratio 1.8–2.2) | Positive(ratio >2.2) |
| 0 | 67 | 1 (1.5%) | 0 |
| 1+ | 38 | 1 (2.6%) | 0 |
| 2+ | 15 | 0 | 2 (13.7%) |
| 3+ | 13 | 0 | 10 (76.9%) |