Table 2

Mutation profile of cell lines

Cell lineBRAFKRASPIK3CACDC4
C125WTK117NWTWT
C32WTWTWTR278*
C80WTA146VWTWT
C84WTG12A†WTWT
Caco2WTWTWTWT
COLO201V600EWTWTWT
COLO205V600EWTWTWT
COLO320DMWTWTWTWT
DLD1WTG13DE545KWT
D549N
GP2DT529AG12DH1047LH580R
HCA7WTWTWTR479*
HCA46WTWTE542KWT
HCT116WTG13DH1047RWT
HRA-19WTWTE542KWT
HT29V600EWTP449TWT
HT55N581YWTWTWT
HuTu80WTWTWTWT
LoVoWTG13DWTR505C
LS1034V600EWTH1047RWT
RKOV600EWTH1047RWT
SKCO-1WTG12V†WTWT
SW1116WTG12AWTWT
SW1222WTA146V†WTWT
SW480WTG12VWTWT
SW620WTG12VWTWT
SW837WTG12CWTL403fs*
SW948WTQ61LE542KWT
VACO10MSWTQ61LWTR505H
VACO5V600EWTR38SWT
H1047R
  • * Nonsense mutation.

  • Homozygous mutation. Data for KRAS and BRAF have been previously reported.18

  • fs, frameshift; WT, wild-type.