Table 3

Association between clinical and immune parameters

Immune parameterCongenital heart disease (no, n=13; yes, n=44)Palatopharyngeal (no, n=45; yes, n=12)Hypoparathyroidism (no, n=35; yes, n=19)
Abs CD3No: 1276 (951–2060)No: 1310 (902–1876)No: 1430 (1220–2020)
Yes: 1320 (836–1825)Yes: 1285 (773–2015)Yes: 820 (600–1410)*
RR: 1.2 (0.6 to 2.4)RR: 0.9 (0.5 to 1.7)RR: 0.5 (0.3 to 0.9)†
Abs CD4No: 663 (521–1463)No: 709 (550–1082)No: 1007 (556–1566)
Yes: 860 (551–1166)Yes: 871 (578–1657)Yes: 512 (428–860)*
RR: 1.4 (0.6 to 3.9)RR: 1.7 (0.8 to 3.8)RR: 0.3 (0.1 to 0.7)†
Abs CD8No: 435 (304–743)No: 517 (288–686)No: 675 (456–813)
Yes: 463 (289–678)Yes: 400 (318–752)Yes: 290 (217–550)*
RR: 1.7 (0.7 to 4.6)RR: 1.0 (0.5 to 2.2)RR: 0.3 (0.1 to 0.7)†
Abs CD19No: 824 (495 – 1,351)No: 673 (456–1043)No: 675 (456–870)
Yes: 680 (412–1000)Yes: 680 (449–950)Yes: 980 (462–1987)*
RR: 1.0 (0.4 to 2.7)RR: 0.9 (0.4 to 1.9)RR: 2.6 (1.0 to 7.0)†
Abs CD56No: 397 (354–440)No: 354 (215–608)No: 378 (243–608)
Yes: 348 (236–612)Yes: 378 (284–860)Yes: 263 (213–782)
RR: 1.0 (0.1 to 7.7)RR: 1.2 (0.5 to 3.6)RR: 0.9 (0.3 to 2.7)
PHANo: 31814 (23520–42456)No: 29167 (23651–52449)No: 33245 (28808–46492)
Yes: 28802 (20377–39868)Yes: 33245 (19335–45747)Yes: 24186 (6882–33419)*
RR: 1.0 (0.4 to 2.2)RR: 1.0 (0.5 to 2.0)RR: 0.4 (0.2 to 0.7)†
Age at test (months)No: 10 (5–24)No: 14 (5–45)No: 15 (9–51)
Yes: 15 (5–45)Yes: 17 (8–24)Yes: 10 (3–27)
  • Absolute (Abs) cell count is given as cells (×106/l); PHA mitogen response is given as cpm. Values for ‘Yes’ and ‘No’ are median (interquartile range),

  • * p<0.05 by Mann–Whitney U test. Values for RR are relative risk (95% CI),

  • p<0.05 for multivariate Cox regression analysis with control (no infections) as reference group and ‘age of test’ as covariant.