Table 3

Fold-difference values for 88 genes in each of eight subtypes (A–H) in 114 subtyped patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Genes without values for the subtypes are those for which there was missing data for one or more subtypes. Bold type indicates genes targeted by existing drugs and those CFS/ME subtypes in which fold-difference values of 1.5 were found

Gene symbolGenbank accessionCFS/ME subtype
ABCDEFGH
ABCD4NM_0203231.400.600.814.4010.617.021.320.93
ACTR3NM_00572110.178.034.3425.7313.956.7527.575.35
AKAP10NM_0072023.833.251.688.395.596.614.891.64
ANAPC11NM_0164762.532.664.343.741.594.162.27
ANAPC5NM_0162371.131.264.491.920.780.002.962.95
APPNM_2014130.631.731.420.564.640.840.842.58
ARL4CNM_0057376.627.402.725.857.828.766.682.81
ARPC5NM_0057172.550.811.535.654.873.414.923.01
ARSDNM_0016690.641.171.514.602.620.260.122.19
ATP6V1C1NM_0016951.993.803.382.432.060.723.634.55
BCORNM_0177451.422.221.782.306.521.132.652.57
BMP2KNM_1988928.964.832.6216.427.763.7811.572.06
BRMS1NM_0153991.314.382.441.534.627.062.573.83
CD2BP2NM_0061103.891.372.216.774.521.335.993.55
CD47NM_1987932.606.903.373.664.060.954.132.75
CEP350NM_0148103.504.473.665.304.501.225.042.04
CITED2NM_0060796.436.841.974.956.024.405.503.42
CMTM6NM_0178013.103.700.6910.047.814.771.710.73
CREBBPNM_0043807.111.621.0913.345.462.618.993.62
CRKNM_0168231.835.571.262.824.891.032.252.02
CTBP1NM_0013284.954.981.058.6215.443.432.422.73
CXCR4NM_00346713.472.182.0328.1017.571.4810.293.57
EBI2NM_0049515.671.412.3114.935.990.760.424.47
EGR1NM_0019550.492.852.420.300.271.001.982.96
EGR3NM_0044210.951.330.465.361.390.98
EIF2B4NM_1721951.440.521.336.003.480.151.692.08
EIF3S10NM_0037501.434.422.101.721.481.252.836.16
EIF4G1NM_1982411.133.473.520.991.392.304.5314.27
EIF4G3NM_0037602.400.790.775.4627.421.093.621.55
ETS1NM_00523835.124.634.1652.6530.3617.5424.176.91
FAM126BNM_1738222.040.630.9110.185.512.591.310.71
FNTANM_0020271.395.722.993.885.072.147.884.06
GABARAPL1NM_0314126.086.423.372.938.492.586.235.74
GABPANM_00203111.968.5621.933.105.7125.8313.3855.99
GCN1L1NM_0068360.801.401.910.445.851.131.592.38
GLTSCR2NM_0157103.682.460.534.946.984.0710.280.80
GNASNM_0804251.721.131.813.623.181.963.472.20
GSNNM_1982521.731.271.693.822.361.643.515.81
GTF2A2NM_0044920.710.531.210.532.190.481.650.87
HIF1ANM_0015302.040.870.825.144.221.664.651.35
IFNAR1NM_0006291.860.170.793.555.531.417.170.91
IL10RANM_0015581.122.680.742.311.011.76
IL6RNM_0005652.192.472.782.67
IL6STNM_0021842.611.494.813.143.072.673.76
IL7RNM_0021851.430.911.661.462.061.33
JAK1NM_0022279.727.843.2928.889.8011.1718.756.19
KHSRPNM_0036850.421.030.910.611.150.751.071.62
MAPK9NM_1390701.161.621.681.830.002.51
METTL3NM_0198520.811.380.641.722.921.081.810.68
MRPL23NM_0211342.340.971.234.154.201.562.562.06
MRPS6NM_0324762.030.922.933.057.751.771.952.00
MRRFNM_13877710.1113.303.962.039.281.339.707.34
MSNNM_0024443.201.661.819.477.863.138.582.12
MTMR6NM_0046853.7111.732.617.737.332.6714.972.58
NFKB1NM_0039983.740.910.658.836.514.107.301.55
NHLH1NM_00558926.3237.9249.0966.3951.25126.29
NR1D2NM_0051261.402.314.573.691.272.502.29
NTENM_0067021.750.310.893.924.371.303.871.43
NUFIP2NM_0207721.551.901.812.832.101.843.502.31
PAPOLANM_0326320.470.520.290.794.730.581.250.32
PDCD2NM_0025983.833.442.945.005.745.885.367.37
PDCD6NM_0132321.962.722.532.164.792.692.852.16
PEX16NM_0048132.1016.102.048.885.920.002.902.80
PGM2NM_0182903.233.622.165.995.724.896.133.36
PIK3R1NM_1815232.064.550.587.177.310.955.480.82
PKN1NM_2135602.253.761.276.676.092.398.142.84
POLR2GNM_0026961.095.582.061.916.012.603.822.91
PPP2R5CNM_0027192.782.621.289.506.141.637.870.84
PRKAA1NM_0062512.144.103.423.534.176.877.133.11
PRKAR1ANM_0027342.051.852.564.143.662.416.355.41
PUM2NM_0153172.811.690.872.855.041.493.842.22
RAP2CNM_0211832.692.564.755.3525.2810.611.95
REPIN1NM_0134002.373.853.121.926.628.537.066.52
RNF141NM_164223.640.642.109.8511.456.0810.832.09
SELENBP1NM_0039447.889.513.4622.187.542.847.655.70
SFXN1NM_0227541.373.461.581.351.401.671.991.72
SHPRHNM_1730820.821.070.217.170.000.64
SNAP23NM_0038253.460.451.8912.6213.334.1510.191.43
SORL1NM_0031051.401.911.602.011.522.47
SOS1NM_0056330.700.811.691.090.291.610.90
TAF11NM_0056430.561.351.052.130.000.211.23
TCF3NM_0032002.000.941.082.833.963.542.522.65
TDP1NM_0183191.605.501.384.8011.550.964.24
TNFRSF1ANM_00106511.964.071.3618.0113.253.3017.812.06
UBTFNM_0142332.883.591.826.036.464.8110.916.44
USP38NM_0325572.660.717.404.277.182.941.02
WAPALNM_0150452.975.133.632.781.246.042.97
WDR26NM_0251600.840.090.632.181.530.802.741.23