Table 1

Patient demographics and tumour characteristics for the first 254 patients undergoing GeneSearch intraoperative molecular analysis of sentinel nodes

Patient characteristicn%Total
Histopathological tumour typeDCIS177256
Invasive ductal18773
Invasive lobular197
Mixed218
Other special type125
Histopathological lymph node statusNegative18472256
Positive7228
Tumour sizeTis177256
T113954
T27830
T352
Multifocal1345
Other (T4=1, pCR=2, MP=1)2
Tumour gradeTis177256
13714
214255
35923
MP1<1
Oestrogen receptor statusPositive21182256
Negative3514
Unknown/NA104256
Progesterone receptor statusPositive19375
Negative5321
Unknown/NA104
HER-2 statusPositive2911256
Negative19275
Indeterminate on IHC229
Unknown/NA135
  • There were five bilateral breast cancers, but three patients were excluded (n=251 patients; 256 sentinal node biopsies).

  • DCIS, ductal carcinoma in situ; IHC, immunohistochemistry; NA, not ascertained (as oestrogen receptor, progesterone receptor and HER-2 status was not always obtained for DCIS); pCR, complete pathological response to neo-adjuvant chemotherapy; MP, malignant phylloides.