Table 3

Fluorescence in situ hybridisation for p16/CDKN2A gene copy number in malignant mesothelioma

	Homozygous deletion^*	Hemizygous deletion^‡	Amplification^†	Normal diploid	Total
Epithelioid	19	5	2	16	42
Sarcomatoid	0	0	0	1	1
Biphasic	4	5	0	2	11
Total	23 (43%)	10 (18%)	2 (4%)	19 (35%)	54

↵* >10% of tumour cells show 0SpO/2SpG.
↵† At least 10% of tumour cell nuclei show SpO/SpG ratio ≥2.
↵‡ >15% of tumour cells show 1SpO/2SpG or >44% show 1SpO/1SpG.