Clinicopathological characteristics of the carcinomas with equivocal (2+) HER2 immunostaining
Variable* | n | % | |
Age (years) | N=345 | ||
<50 | 57 | 16.5 | |
≥50 | 288 | 83.5 | |
Size (mm) | N=278 | ||
≤20 | 143 | 51.4 | |
>20 | 135 | 48.6 | |
Histological type | N=345 | ||
Ductal | 302 | 87.5 | |
Lobular | 38 | 11.0 | |
Others (tubular, medullary) | 5 | 1.4 | |
Histological grade (BRE) | N=323 | ||
1 | 43 | 13.3 | |
2 | 201 | 62.2 | |
3 | 79 | 24.5 | |
Oestrogen receptor | N=344 | ||
Positive (>10% of tumour cells) | 299 | 86.9 | |
Negative (<10% of tumour cells) | 45 | 13.1 | |
Progesterone receptor | N=344 | ||
Positive (>10% of tumour cells) | 241 | 70.1 | |
Negative (<10% of tumour cells) | 103 | 29.9 | |
Ki-67 | N=225 | ||
Low (<20% of tumour cells) | 122 | 54.2 | |
High (>20% of tumour cells) | 103 | 45.8 | |
pT stage | N=278 | ||
pT1 | 143 | 51.4 | |
pT2 | 122 | 43.9 | |
pT3 | 11 | 4.0 | |
pT4 | 2 | 0.7 | |
Nodal status | N=264 | ||
pN− | 136 | 51.5 | |
pN+ | 128 | 48.5 |
↵* For a subset of carcinomas, not all clinicopathological characteristics were available. BRE score, Bloom–Richardson–Elston score.