Table 5

EpCAM expression in metastases of different tumour origin

Tumour type (no. of samples)No EpCAM overexpression*EpCAM overexpression*
No expression (TIS 0)Weak expression (TIS 1–4)Moderate expression (TIS 6, 8)Intense expression (TIS 9, 12)
Liver metastases from colorectal cancer (18)00317001583
CNS metastases from breast cancer (15)17533427533
Peritoneal metastases from colon, ovary, pancreatobiliary and gastric cancer (22)147321045419
Lymph node metastases from breast cancer (5)240120120120
Lymph node metastases from colon cancer (48)00510483981
  • EpCAM expression was determined by immunohistochemistry.

  • * EpCAM overexpression defined by Gastl et al3.

  • CNS, central nervous system; EpCAM, epithelial cell adhesion molecule; TIS, total immunostaining score.