Table 4

Multivariate survival analyses

Parameter	Category	DSS		MEFS		LRFS
Parameter	Category	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
Rsf1	Low expression (0+∼2+)	1 (2.309 to 8.548)	<0.0001^*	1 (1.590 to 6.379)	0.0011^*	1 (2.203 to 12.690)	0.0002^*
Rsf1	Overexpression (3+∼4+)	4.442 (–)	<0.0001^*	3.185 (–)	0.0011^*	5.287 (–)	0.0002^*
Nodal status (N)	N0–N1	1 (1.014 to 3.971)	0.0454^*	1 (0.710 to 2.925)	0.3114	1 (0.869 to 5.021)	0.0998
Nodal status (N)	N2–N3	2.007 (–)	0.0454^*	1.441 (–)	0.3114	2.089 (–)	0.0998
Primary tumour (T)	T1–T2	1 (0.896 to 2.756)	0.1134	1 (1.063 to 3.827)	0.0319^*	1 (0.918 to 4.158)	0.0823
Primary tumour (T)	T3–T4	1.583	0.1134	2.017 (–)	0.0319^*	1.953 (–)	0.0823
Histological grade	Keratinised/non-keratinised	1 (0.808 to 2.273)	0.2496	1 (0.856 to 3.175)	0.1353
Histological grade	Undifferentiated	1.355 (–)	0.2496	1.648 (–)	0.1353
Therapeutic response	Complete response			1 (0.844 to 5.572)	0.1081
Therapeutic response	Partial response			2.168 (–)	0.1081

* and bold type, Statistically significant.
DSS, disease-specific survival; LRFS, local recurrence-free survival; MFS, metastasis-free survival.