Reference (first author) | TAB | MIC or OSNA+ | MIC | OSNA+ | Concordant MIC and OSNA+ | MIC overrated by OSNA++ | MIC underrated by OSNA− | OSNA+ overrated as MAC | OSNA+ underrated as ITC/NEG |
Tsujimoto12 | 2 | 15 | 5 | 13 | 3 | 0 | 2 | 6 | 4 |
Visser24 | 7 | 26 | 11 | 20 | 5 | 4 | 2 | 2 | 13 |
Schem25 | 13 | 33 | 9 | 24 | 0 | 7 | 2 | 7 | 17 |
Snook18 | 17 | 30 | 12 | 27 | 9 | 1 | 2 | 8 | 10 |
Feldman27 | 19 | 81 | 43 | 50 | 12 | 9 | 22 | 9 | 29 |
Bernet28 | 8 | 14 | 9 | 10 | 5 | 2 | 2 | 1 | 4 |
Le Frere-Belda14 | 22 | 47 | 18 | 32 | 3 | 6 | 9 | 5 | 24 |
All | 88 | 246 | 107 | 176 | 37 | 29 | 41 | 38 | 101 |
ITC, isolated tumour cells/clusters; MAC, macrometastasis (>2 mm); MIC, micrometastasis; NEG, negative by histology; OSNA+, one-step nucleic acid amplification positive with 250–5000 copies/μl; OSNA++, one-step nucleic acid amplification positive with >5000 copies/μl; OSNA−, one-step nucleic acid amplification negative with <250 copies/μl; TAB, tissue allocation bias.