Peritumour stromal expression in encapsulated papillary carcinoma (EPC), ductal carcinoma in situ (DCIS) and invasive carcinoma
| Biomarker | EPC n (%) | DCIS n (%) | Invasive carcinoma n (%) |
| MMP-1 | 0 (0) | 1 (10%) | 19 (14) |
| MMP-2 | 3 (18) | 2 (20) | 17 (12) |
| MMP-7 | 3 (18) | 1 (10) | 19 (14) |
| MMP-9 | 2 (12) | 1 (10) | 27 (19) |
| TGF-ß1 | 1 (6) | 0 (0) | 18 (13) |
| VEGF | 2 (12) | 0 (0) | 22 (16) |
| E-cadherin | 0 | 0 | 0 |
Stromal expression in the invasive carcinomas was assessed in the peritumoural and/or intratumoural stroma within the cores of tissue prepared as tissue microarrays. Stromal expression is reported as positive and negative.
MMP, matrix metalloproteinase; TGF, transforming growth factor receptor; VEGF, vascular endothelial growth factor.