Table 3

Classification of participants by clinical outcome and characteristics of lesions and median faecal haemoglobin (ng Hb/ml).

OutcomeNumberMedian faecal haemoglobin (ng Hb/ml) and (95% CI)p Value (comparison is between enclosed outcomes)
No pathology170858 (747 to >1000)
Diverticular disease104803 (706 to 999)
Inflammatory bowel disease34886 (661 to >1000)
Haemorrhoids48>1000 (720 to >1000)
Hyperplastic polyps40899 (642 to >1000)
Other non-neoplastic pathology67990 (680 to >1000)
 All non-neoplastic pathology463885 (785 to 991)0.04
 All neoplastic pathology350>1000 (958 to >1000)
All adenoma311988 (855 to >1000)
 High-risk adenoma190>1000 (>1000 to >1000)0.006
 Low-risk adenoma119760 (652 to 921)
Adenoma histology*
 High-grade dysplasia57753 (574 to >1000)0.009
 Low-grade dysplasia252562 (524 to 620)
 Villous155583 (530 to 665)0.07
 Non-villous128565 (509 to 606)
Size (diameter)†
 <10 mm134756 (652 to 846)<0.0001
 ≥10 mm174>1000 (>1000 to >1000)
Number‡
 <3259988 (818 to >1000)0.64
 ≥351>1000 (770 to >1000)
Adenoma site
 Proximal colon69792 (653 to 996)0.08
 Distal colon242>1000 (924 to >1000)
Cancer39>1000 (>1000 to >1000)
 Dukes’ stage
  A or B23>1000 (725 to >1000)0.08
  C or higher13>1000 (>1000 to >1000)
 Tumour site
  Proximal colon12>1000 (>1000 to >1000)0.32
  Distal colon27>1000 (996 to >1000)
 Cancer type§
  Polyp6773 (518 to >1000)0.04
  Other28>1000 (>1000 to >1000)
  • *Degree of dysplasia was not available for two participants and adenoma type was not available for 28 participants.

  • †Three participants did not have adenoma size reported and were excluded.

  • ‡One participant did not have adenoma number reported.

  • §Five cancers not defined either as polyp or more invasive.