Demographic, clinical, and laboratory characteristics of IgMN subgroups
| Parameters | Group 1 n=15 (75%) | Group 2 n=5 (25%) | p Value |
|---|---|---|---|
| At presentation | |||
| Age | 5.0 (3.5–10) (CI 4.5 to 8.6) | 9.0 (7.5–12) (CI 6.6 to 12.5) | 0.119 |
| Boys | 11 (73.3%) | 4 (80%) | |
| Girls | 4 (26.6%) | 1 (20%) | |
| M:F ratio | 3:1 | 4:1 | 0.63 |
| SBP, mm Hg | 112.0 (110–130) (CI 110.4 to 124) | 138 (124–140) (CI 122 to 144) | 0.019 |
| DBP, mm Hg | 82.0 (72–90) (CI 74.26 to 85.8) | 92.0 (78–95) (CI 76.3 to 98.9) | 0.197 |
| Total proteins, g/dl | 3.80 (3.6–4.0) (CI 3.6 to 4.0) | 3.8 (3.5–4.0) (CI 3.4 to 4.1) | 0.86 |
| Serum albumin, g/dl | 1.80 (1.7–2.2) (CI 1.7 to 2.2) | 1.90 (1.5–1.9) (CI 1.3 to 2.1) | 0.93 |
| Blood urea, mg/dl | 18.0 (16–20) (CI 15.5 to 23.9) | 34.0 (26–42) (CI 23.5 to 44.4) | 0.004 |
| Serum creatinine, mg/dl | 0.42 (0.33–0.6) (CI 0.36 to 0.58) | 0.8 (0.70–1.19) (CI 0.55 to 1.2) | 0.002 |
| At last follow-up | |||
| Duration of follow up, months | 7 (6–12) (CI 6.79 to 12.4) | 18 (12–22) (CI 10.7 to 23.6) | 0.015 |
| SBP, mm Hg | 120 (112–120) (CI 113.7 to 122) | 130 (125–131) (CI 123.6 to 133) | 0.004 |
| DBP, mm Hg | 74.0 (70–80) (CI 72.7 to 79.8) | 88 (78.5–92.5) (CI 76.4 to 95.5) | 0.019 |
| Serum creatinine, mg/dl | 0.66 (0.46–0.73) (CI 0.54 to 0.74) | 1.20 (0.77–1.7) (CI 0.62 to 1.82) | 0.11 |
| Proteinuria, % | 6.7 | 100 | 0.001 |
All values are in median (IQR) except where stated otherwise.
DBP, diastolic blood pressure; IgMN, IgM nephropathy; SBP, systolic blood pressure.