Table 1

Demographic, clinical, and laboratory characteristics of IgMN and MCD groups

ParametersIgMN
n=34
MCD
n=20
p Values
At presentation
Age, years4.5 (3–8.0) (CI 3.8 to 7.1)4.0 (2–6.1) (CI 3.6 to 5.9)0.413
Boys, n (%)15 (75%)19 (55.8%)
Girls, n (%)5 (25%)15 (44.1%)
M:F ratio3:11.2:10.244
Total proteins, g/dl3.8 (3.6–4.0) (CI 3.5 to 3.9)3.7 (3.4–4.0) (CI 3.5 to 3.9)0.523
Serum albumin, g/dl2.00 (1.8–2.5) (CI 1.9 to 2.3)1.9 (1.7–2.6) (CI 1.9 to 2.3)0.921
Blood urea, mg/dl16.5 (14.2–18) (CI 14.5 to 21.2)12. (9.0–18) (CI 11.9 to 15.9)0.015
Serum creatinine, mg/dl0.62 (0.32–0.68) (CI 0.45 to 0.71)0.42 (0.33–0.49) (CI 0.36 to 0.47)0.037
SBP, mm Hg116 (110–123.5) (CI 110.9 to 119.9)117 (100–124) (CI 112.8 to 119.1)0.786
DBP, mm Hg76 (70.5–80) (CI 71.2 to 77.4)74.5 (70–84) (CI 74.4 to 79.4)0.274
At last follow-up
SBP, mm Hg111 (110–120) (CI 110.7 to 118.4)110 (100–120) (CI 107.4 to 113.8)0.095
DBP, mm Hg73 (72–80) (CI 73.1 to 78.5)72 (68–80) (CI 70.2 to 75.5)0.159
Serum creatinine, mg/dl0.62 (0.46–0.81) (CI 0.53 to 0.81)0.39 (0.33–0.52) (CI 0.33 to 0.52)0.000
Response to CNI, %75940.043
  • CNI, calcineurin inhibitors; DBP, diastolic blood pressure; IgMN, IgM nephropathy; MCD, minimal change disease; SBP, systolic blood pressure.