TableĀ 4

Features favouring infective colitis over IBD

ReliableAbsence of features of IBDEL1a RGA1 25 26 33 58
Preservation of normal crypt architecture1 25 32
No crypt branching18
Parallel crypts4
Absence of basal plasmacytosis32
Less reliable/limited dataInflammation in upper half of lamina propria/increased cellularity of upper two-thirds of mucosaEL1b RGD4 58
Acute inflammation (rather than chronic/mixed inflammation) of the lamina propria18
Superficial (rather than basal) giant cells25
Superficial (rather than deep) crypt abscesses25
Cystic crypt abscesses25
  • EL, evidence levels; IBD, inflammatory bowel disease.