Factor | Characteristics | S100A4 expression | Total | p Value | |
---|---|---|---|---|---|
No/weak | Strong | ||||
Gender | Male | 87 (73.1%) | 32 (26.9%) | 119 | 0.87 |
Female | 54 (75.0%) | 18 (25.0%) | 72 | ||
Growth pattern | Polypoid | 27 (79.4%) | 7 (20.6%) | 34 | 0.36 |
Nodular | 7 (58.3%) | 5 (41.7%) | 12 | ||
Infiltrative | 100 (73.0%) | 37 (27.0%) | 137 | ||
Histological subtype | Tubular adenocarcinoma | 128 (73.1%) | 47 (26.9%) | 175 | 0.69 |
Mucinous adenocarcinoma | 6 (75.0%) | 2 (25.0%) | 8 | ||
Signet ring cell carcinoma | 4 (100.0%) | 0 | 4 | ||
Undifferentiated carcinoma | 3 (75.0%) | 1 (25.0%) | 4 | ||
Differentiation | Well differentiated | 34 (82.9%) | 7 (17.1%) | 41 | 0.42 |
Moderately differentiated | 73 (69.5%) | 32 (30.5%) | 105 | ||
Poorly differentiated | 31 (75.6%) | 10 (24.4%) | 41 | ||
Undifferentiated | 3 (75.0%) | 1 (25.0%) | 4 | ||
pT classification | pT1+pT2 | 16 (100.0%) | 0 | 16 | <0.05*† |
pT3 | 45 (72.6%) | 17 (27.4%) | 62 | ||
pT4 | 78 (70.9%) | 32 (29.1%) | 32 | ||
Lymph node metastasis‡ | Absent (pN0) | 70 (83.3%) | 14 (16.7%) | 84 | 0.01* |
Present (pN1+pN2) | 58 (65.2%) | 31 (34.8%) | 89 | ||
Pancreas invasion | Absent | 94 (76.4%) | 29 (23.6%) | 123 | 0.30 |
Present | 47 (69.1%) | 21 (30.9%) | 68 | ||
Other loop invasion | Absent | 136 (73.1%) | 50 (26.9%) | 186 | 0.33 |
Present | 5 (100.0%) | 0 | 5 | ||
Retroperitoneal seeding | Absent | 131 (74.0%) | 46 (26.0%) | 177 | 0.76 |
Present | 10 (71.4%) | 4 (28.6%) | 14 | ||
Perineural invasion | Absent | 102 (79.1%) | 27 (20.9%) | 129 | 0.02* |
Present | 39 (62.9%) | 23 (37.1%) | 62 | ||
Vascular invasion | Absent | 105 (74.5%) | 36 (25.5%) | 141 | 0.71 |
Present | 36 (72.0%) | 14 (28.0%) | 50 | ||
Lymphatic invasion | Absent | 74 (77.1%) | 22 (22.9%) | 96 | 0.33 |
Present | 67 (70.5%) | 28 (29.5%) | 95 |
*Significant at p<0.05.
†Original p=0.045.
‡Calculated only cases with available information of examined lymph node.