Table 3

Multivariable analysis of small intestine adenocarcinoma

Variable	HR	95% CI		p Value
Variable	HR	Lower	Upper	p Value
S100A4 expression	1.80	1.13	2.86	0.01*
Proximal vs distal	1.52	0.93	2.46	0.09
Histological type				0.24
Tubular adenocarcinoma	1	–	–	–
Mucinous adenocarcinoma	1.44	0.59	3.50	0.42
Signet ring cell carcinoma	3.64	0.75	17.70	0.11
Undifferentiated carcinoma	2.74	0.67	11.16	0.16
Differentiation				0.78
Well differentiated	1	–	–	–
Moderately differentiated	0.82	0.45	1.49	0.51
Poorly differentiated	0.90	0.44	1.85	0.77
Undifferentiated carcinoma	2.24	0.56	8.98	0.25
pT classification				0.11
pT1+pT2	1		–	–
pT3	0.53	0.19	1.49	0.23
pT4	0.89	0.32	2.46	0.83
pN classification				0.35
pN0	1	–	–	–
pN1	1.45	0.85	2.47	0.17
pN2	1.43	0.74	2.78	0.29
Other loop invasion	3.78	0.76	18.82	0.11
Retroperitoneal seeding	2.04	0.94	4.44	0.07
Perineural invasion	1.07	0.67	1.71	0.79
Vascular invasion	0.96	0.57	1.62	0.88
Lymphatic invasion	1.76	0.99	3.11	0.05
Sporadic adenoma	0.21	0.05	0.91	0.04*
Peritumoral dysplasia	0.49	0.23	1.04	0.06