Clinicopathological factors according to the detection of BM involvement by PCR-based clonality in 96 cases of follicular lymphoma
| PCR-based clonality | |||||
|---|---|---|---|---|---|
| Variables | n | No involvement (%) | Involvement (%) | p Value* | |
| Sex | |||||
| Female | 59 | 36 (61.0) | 23 (39.0) | ||
| Male | 37 | 27 (73.0) | 10 (27.0) | 0.230 | |
| Age (years) | |||||
| ≤60 | 42 | 30 (71.4) | 12 (28.6) | ||
| >60 | 54 | 33 (61.1) | 21 (38.9) | 0.291 | |
| WHO grade | |||||
| 1 | 35 | 20 (57.1) | 15 (42.9) | ||
| 2 | 30 | 21 (70.0) | 9 (30.0) | ||
| 3A and 3B | 31 | 22 (71.0) | 9 (29.0) | 0.447 | (1, 2 vs 3) |
| BM morphology | |||||
| No involvement | 67 | 54 (80.6) | 13 (19.4) | ||
| Involvement | 29 | 9 (31.0) | 20 (69.0) | <0.001 | |
| Clinical stage | |||||
| I | 16 | 14 (87.5) | 2 (12.5) | ||
| II | 16 | 16 (100.0) | 0 (0.0) | ||
| III | 34 | 24 (70.6) | 10 (29.4) | ||
| IV | 30 | 9 (30.0) | 21 (70.0) | <0.001 | (I–III vs IV) |
| FLIPI score | |||||
| Low (0–1) | 45 | 37 (82.2) | 8 (17.8) | ||
| Intermediate (2) | 23 | 14 (60.9) | 9 (39.1) | ||
| High (≥3) | 28 | 12 (42.9) | 16 (57.1) | 0.003 | (0–2 vs ≥3) |
*Pearson's χ2 test.
BM, bone marrow; FLIPI, Follicular Lymphoma International Prognostic Index.